Question 1

Neil has accidentally ingested a toxic chemical, which has made him unconscious and will soon kill him. Which route of administration would emergency physicians most likely use to administer an antidote for the toxin?

Accepted Answer

A)   intravenous
B)   oral
C)   topical
D)   rectal
E)   nasalF) A) and C)
G) None of the above

Question 2

Which of the following is true of the cholinergic systems?

Accepted Answer

A)   Hemicholium blocks the release of acetylcholine from peripheral neurons.
B)   Acetylcholinesterase blocks the reuptake of choline into the presynaptic terminal.
C)   The drug atropine is used to treat myasthenia gravis.
D)   Muscarinic receptors are more numerous than nicotinic receptors in the brain.
E)   Black widow spider venom prevents the release of acetylcholine.F) A) and B)
G) A) and E)

Question 3

Jackson is doing research in which she examines whether a drug effect is different depending on whether the drug is given orally or rectally. We might say that she is doing a study involving

Accepted Answer

A)   neurotherapy.
B)   neurochemistry.
C)   behavioral neuroscience.
D)   pharmacokinetics.
E)   neuropharmacology.F) A) and B)
G) B) and D) D

Question 4

________ refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

Accepted Answer

A)   Pharmacotherapy
B)   Pharmacokinetics
C)   Drug metabolism
D)   Pharmacodynamics
E)   NeurobotanyF) A) and D)
G) All of the above

Question 5

Glutamate, GABA, and glycine are important because these are

Accepted Answer

A)   the major excitatory neurotransmitters in the CNS.
B)   known to be solely inhibitory in the brain.
C)   the predominant neuromodulators in the spinal cord.
D)   the most common neurotransmitters in the CNS.
E)   involved in Parkinson's disease.F) C) and D)
G) C) and E)

Question 6

Which of the following is a correct match between a drug and its effect on GABA function?

Accepted Answer

A)   muscimol; agonist at the GABAB receptor
B)   picrotoxin; indirect antagonist of the GABAA receptor
C)   diazepam; reduces the activity of GABAA receptors
D)   baclofen; antagonist at the GABAA receptor
E)   nicotine; agonist at the GABAA receptorF) A) and B)
G) C) and E)

Question 7

________ refers to the capacity of a drug molecule to bind to a key site of action.

Accepted Answer

A)   Dissociation
B)   Sensitization
C)   Inactivation
D)   Affinity
E)   ToleranceF) A) and B)
G) A) and C)

Question 8

Which transmitter below induces muscle movement and is the primary transmitter secreted by efferent axons of the central nervous system?

Accepted Answer

A)   acetylcholine
B)   GABA
C)   serotonin
D)   glycine
E)   glutamateF) A) and B)
G) None of the above

Question 9

Drugs that block histamine receptors produce

Accepted Answer

A)   Parkinsonism.
B)   delusions.
C)   drowsiness.
D)   REM sleep.
E)   arousal.F) A) and C)
G) C) and D)

Question 10

The drug reserpine

Accepted Answer

A)   was used medically to treat high blood pressure.
B)   is used to treat myasthenia gravis.
C)   blocks the storage of monoamines in vesicles.
D)   can produce Parkinson's disease in some persons.
E)   interferes with the synthesis of dopamine.F) A) and B)
G) B) and E)

Question 11

A drug that blocks acetylcholinesterase in brain would be expected to

Accepted Answer

A)   permanently damage brain cholinergic neurons.
B)   decrease the amount of acetylcholine in the synapse.
C)   increase the synaptic levels of acetylcholine.
D)   alter the activity of the cholinergic autoreceptors.
E)   reduce the rate of reuptake of acetylcholine into glial cells.F) C) and E)
G) A) and D)

Question 12

The ________ route of drug administration is commonly used for small laboratory animals such as the rat.

Accepted Answer

A)   intraperitoneal
B)   oral
C)   intravascular
D)   topical
E)   intranasalF) B) and D)
G) B) and C) A

Question 13

Termination of the postsynaptic potential would be expected from a drug or process that acts to

Accepted Answer

A)   increase synthesis of the neurotransmitter molecule.
B)   enzymatically degrade the neurotransmitter molecule.
C)   blocks transport of the neurotransmitter molecule through the axon membrane.
D)   increase the number of postsynaptic receptors.
E)   increase release of the neurotransmitter.F) None of the above
G) D) and E)

Question 14

Which of the following drugs has the largest therapeutic index?

Accepted Answer

A)   heroin
B)   Valium
C)   alcohol
D)   barbiturates
E)   a mixture of barbiturates and alcoholF) A) and E)
G) A) and B)

Question 15

Drugs that inactivate monoamine oxidase B would be expected to

Accepted Answer

A)   also block D2 receptors.
B)   increase the release of dopamine in response to the arrival of an action potential at the terminal buttons.
C)   make the dopamine transporter run in reverse.
D)   cause the release of serotonin into the synaptic cleft.
E)   increase the release of acetylcholine in response to the arrival of an action potential at the terminal buttons.F) A) and B)
G) A) and C) B

Question 16

Acetylcholine is produced when ________ accepts an acetate ion from coenzyme A and transfers it to a choline molecule.

Accepted Answer

A)   acetylcholinesterase
B)   coenzyme A
C)   muscarine transferase
D)   choline acetyltransferase
E)   nicotine synthaseF) A) and D)
G) C) and D)

Question 17

2- Memory impairment results from the effects of THC on CB1 receptors located in the ________.

Accepted Answer

The answer of 2- Memory impairment results from the effects...

Question 18

The neostriatum consists of the

Accepted Answer

A)   putamen and the hippocampus.
B)   ventral tegmental area and the overlying pons.
C)   cerebellum and the nucleus accumbens.
D)   caudate nucleus and the putamen.
E)   amygdala and the hippocampus.F) A) and B)
G) A) and C)

Question 19

Cholinergic neurons within the ________ are thought to ________.

Accepted Answer

A)   basal forebrain; control the electrical activity of the thalamus
B)   dorsolateral pons; facilitate learning
C)   medial septum; elicit most of the aspects of REM sleep
D)   cerebellum; elicit motor movements
E)   dorsolateral pons; elicit most of the aspects of REM sleepF) A) and E)
G) B) and C)

Question 20

________ refers to a diminished drug effect with repeated injection of a constant drug dose.

Accepted Answer

The answer of ________ refers to a diminished drug effect...

Exam 4: Psychopharmacology

Neil has accidentally ingested a toxic chemical, which has made him unconscious and will soon kill him. Which route of administration would emergency physicians most likely use to administer an antidote for the toxin?

Correct AnswerverifiedShow Answer

Which of the following is true of the cholinergic systems?

Correct AnswerverifiedShow Answer

Jackson is doing research in which she examines whether a drug effect is different depending on whether the drug is given orally or rectally. We might say that she is doing a study involving

Correct AnswerverifiedD

________ refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

Correct AnswerverifiedShow Answer

Glutamate, GABA, and glycine are important because these are

Correct AnswerverifiedShow Answer

Which of the following is a correct match between a drug and its effect on GABA function?

Correct AnswerverifiedShow Answer

________ refers to the capacity of a drug molecule to bind to a key site of action.

Correct AnswerverifiedShow Answer

Which transmitter below induces muscle movement and is the primary transmitter secreted by efferent axons of the central nervous system?

Correct AnswerverifiedShow Answer

Drugs that block histamine receptors produce

Correct AnswerverifiedShow Answer

The drug reserpine

Correct AnswerverifiedShow Answer

A drug that blocks acetylcholinesterase in brain would be expected to

Correct AnswerverifiedShow Answer

The ________ route of drug administration is commonly used for small laboratory animals such as the rat.

Correct AnswerverifiedA

Termination of the postsynaptic potential would be expected from a drug or process that acts to

Correct AnswerverifiedShow Answer

Which of the following drugs has the largest therapeutic index?

Correct AnswerverifiedShow Answer

Drugs that inactivate monoamine oxidase B would be expected to

Correct AnswerverifiedB

Acetylcholine is produced when ________ accepts an acetate ion from coenzyme A and transfers it to a choline molecule.

Correct AnswerverifiedShow Answer

2- Memory impairment results from the effects of THC on CB1 receptors located in the ________.

Correct AnswerverifiedShow Answer

The neostriatum consists of the

Correct AnswerverifiedShow Answer

Cholinergic neurons within the ________ are thought to ________.

Correct AnswerverifiedShow Answer

________ refers to a diminished drug effect with repeated injection of a constant drug dose.

Correct AnswerverifiedShow Answer

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D

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A

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B

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Cholinergic neurons within the are thought to .

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